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Symbol Name ID |
Cd81
CD81 antigen MGI:1096398 |
| Darker colors indicate more annotations |
| Human Phenotypes | Chronic decreased circulating total IgG |
Complete or near-complete absence of specific antibody response to tetanus vaccine |
Decreased specific pneumococcal antibody level |
Abnormal B cell count |
Abnormal T cell count |
Autoimmune thrombocytopenia |
Glomerulonephritis |
Recurrent bacterial infections |
Recurrent respiratory infections |
| Disease(s) Associated with CD81 | |||||||||
| common variable immunodeficiency 6 |
| Mouse Phenotypes | decreased B cell proliferation |
increased B cell proliferation |
abnormal T cell proliferation |
abnormal B cell differentiation |
decreased B-1 B cell number |
decreased B-1a cell number |
abnormal B cell morphology |
abnormal microglial cell morphology |
increased IgA level |
decreased IgG1 level |
increased IgG3 level |
decreased IgG level |
increased IgM level |
abnormal T-helper 2 physiology |
abnormal macrophage physiology |
abnormal immune system cell morphology |
decreased susceptibility to type I hypersensitivity reaction |
decreased susceptibility to parasitic infection |
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| Availability | Mouse Genotype | ||||||||||||||||||
| Cd81tm1Geha/Cd81tm1Geha | |||||||||||||||||||
| Cd81tm1Lvy/Cd81tm1Lvy | |||||||||||||||||||
| Cd81tm1Tmiy/Cd81tm1Tmiy | |||||||||||||||||||
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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last database update 04/30/2024 MGI 6.23 |
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